|
ACCURATE
EFFICIENT
RELIABLE
-
Use in confidence in patients with renal disease
-
No “carry over” issues with iron or lipase reagents
-
Diazyme’s Enzymatic homocysteine is the choice of hundreds of laboratories worldwide
CONVENIENT
PRECISION
- Precision according to NCCLS EP-5
Assay Principle The Diazyme enzymatic tHcy assay is based on a novel assay principle that assesses the co-substrate conversion product. In the assay, oxidized Hcy is first reduced to free Hcy which then reacts with a co-substrate, SAM, catalyzed by a homocysteine S-methyltransferase. The co-substrate conversion product is amplified by coupled enzymatic cycling reactions. The tHcy level in the sample is indirectly proportional to the amount of NADH conversion to NAD+ (ΔA340nm). Intended use The Diazyme Homocysteine Enzymatic Assay kit is intended for thein vitro quantitative determination of total L-homocysteine in serum or plasma. The assay can assist in diagnosis and treatment of patients suspected of having hyperhomocysteinemia and homocystinuria.
|
|
|