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ImmunoDOT Autoimmune Panel 1 (25 Test Kit)
ImmunoDOT Autoimmune Panel 1 (25 Test Kit)

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Product Code: 800-5125

ImmunoDOT is a dot-blot assay system combining microwell EIA and western blot advantages. Like microwell, a purified antigen set at a clinically meaningful cutoff is applied to nitrocellulose membrane. Reactivity is detected using the same reagent system used in most western blot assays. Extractable nuclear antigens (ENA) and chicken red blood cells nuclei compose the ANA dot and double-stranded DNA is separately and simultaneously measured. Additionally, if ENA reactivity is present, the test notes which type, RNP/Sm or SS-A/B. This test is accepted as an ANA sceening method.
  • The ImmunoDOT Autoimmunity Screening Panel 1 is an enzyme immunoassay (EIA) test for screenin g and detection of autoantibodies against various specific nuclear an tigens in serum and heparinized whole blood and used as an aid in the diagnosis of autoimmune disorders. This product is intended for use in physician offices and clinical laboratories.

  • Identification of the lupus erythematosus (LE) cell in 1948 provided physicians with a relatively specific laboratory test to aid in the diagnosis of systemic lupus erythematosus (SLE ). More recently, determining the presence or absence of particular autoantibodies influences the confidence with which a diagnosis is made. The ImmunoDOT Autoimmunity Screening Panel 1 detects total antinuclear antibody for specific diagnostically significan t nuclear antigens and measures
    individually antibodies to fi ve common nuclear antigens: deoxyribonucleic acid (DNA), Sjogren's syndrome antigen A (Ro) and antigen B (La), ribonucleoprotein (RNP), and Smith (Sm) antigen.

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